Upregulated myocardial CXCR4-expression after myocardial infarction assessed by simultaneous GA-68 pentixafor PET/MRI

J Nucl Cardiol. 2016 Feb;23(1):131-3. doi: 10.1007/s12350-015-0347-5. Epub 2015 Dec 14.

Authors

C Rischpler¹, S G Nekolla², H Kossmann³, R J Dirschinger³, M Schottelius⁴, F Hyafil², H J Wester⁴, K L Laugwitz³, M Schwaiger²

Affiliations

¹ Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. [email protected].
² Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
³ Medizinische Klinik und Poliklinik I, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
⁴ Pharmazeutische Radiochemie, Technische Universität München, Garching, Germany.

PMID: 26667813
DOI: 10.1007/s12350-015-0347-5

No abstract available

Publication types

Case Reports

MeSH terms

Biomarkers / metabolism
Coordination Complexes / pharmacokinetics*
Humans
Image Interpretation, Computer-Assisted / methods
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Molecular Imaging / methods
Multimodal Imaging / methods
Myocardial Infarction / diagnosis*
Myocardial Infarction / metabolism*
Myocardium / metabolism
Peptides, Cyclic / pharmacokinetics*
Positron-Emission Tomography / methods*
Radiopharmaceuticals / pharmacokinetics
Receptors, CXCR4 / metabolism*
Reproducibility of Results
Sensitivity and Specificity
Tissue Distribution
Up-Regulation

Substances

68Ga-pentixafor
Biomarkers
CXCR4 protein, human
Coordination Complexes
Peptides, Cyclic
Radiopharmaceuticals
Receptors, CXCR4