Aspergillus Vertebral Osteomyelitis Complicating Pulmonary Granuloma in an Immunocompetent Adult

Med Princ Pract. 2016;25(4):394-6. doi: 10.1159/000443310. Epub 2015 Dec 14.

Abstract

Objective: The aim of this report is to describe a case with Aspergillus vertebral osteomyelitis complicating pulmonary granuloma in an immunocompetent adult.

Clinical presentation and intervention: A 53-year-old male patient was found to have lesions on lumbar vertebra 5 months after thoracoscopic resection of pulmonary granuloma that lacked a definite etiology. Three operations on the lumbar lesions were performed successively; however, an Aspergillus infection was not confirmed until hyphae were clearly detected at the last surgery. The patient was treated with voriconazole and recovered well.

Conclusion: This case shows that simultaneous occurrence of granulomatous nodules in the lung and vertebral lesions should raise suspicion of aspergillosis, even in immunocompetent patients.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Aspergillosis / complications*
  • Granuloma / complications*
  • Humans
  • Lumbar Vertebrae / pathology*
  • Lung Diseases / complications*
  • Male
  • Middle Aged
  • Osteomyelitis / complications*
  • Osteomyelitis / microbiology

Substances

  • Antifungal Agents