Polypharmacy among the elderly in the Republic of Srpska: extent and implications for the future

Expert Rev Pharmacoecon Outcomes Res. 2016 Oct;16(5):609-618. doi: 10.1586/14737167.2016.1115347. Epub 2015 Dec 15.

Abstract

The prescribing of medicines is a fundamental component of care for the elderly; however, there is increasing concern with polypharmacy and its impact on morbidity, mortality and costs. As a result, long-term prescription-medicine use and the prevalence of polypharmacy in the elderly in the Republic of Srpska were analyzed. The findings were subsequently used to suggest potential future measures. A retrospective study of all elderly patients during 2005-2010 stratified by age group (three groups), sex and long-term medicine use was performed. Polypharmacy (five or more medicines) increased from 1.4% of the elderly taking medicines long-term to 3.6% by 2010, with 53.6% of elderly taking two or more medicines long-term. The most prevalent diseases were cardiovascular diseases and diabetes. Most prescriptions were in accordance with recent guidelines; however, there was a concern with appreciable prescribing of digoxin and aminophylline. Whilst polypharmacy rates are low in the Republic, the increasing rate is a concern. Further studies are planned.

Keywords: Polypharmacy; Republic of Srpska; cardiovascular disease; drug utilisation; guidelines.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Bosnia and Herzegovina
  • Cardiovascular Diseases / drug therapy
  • Cardiovascular Diseases / epidemiology
  • Diabetes Mellitus / drug therapy
  • Diabetes Mellitus / epidemiology
  • Female
  • Humans
  • Male
  • Polypharmacy*
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians' / standards*
  • Prescription Drugs / administration & dosage*
  • Prevalence
  • Retrospective Studies
  • Time Factors

Substances

  • Prescription Drugs