Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination"

Sci Transl Med. 2015 Dec 16;7(318):318lr4. doi: 10.1126/scitranslmed.aad8657.

Abstract

Multiple risk factors may cause progression to severe dengue.

Publication types

  • Letter
  • Comment

MeSH terms

  • Animals
  • Dengue Virus / metabolism*
  • Endothelial Cells / pathology*
  • Humans
  • Toll-Like Receptor 4 / metabolism*
  • Viral Nonstructural Proteins / immunology*

Substances

  • Toll-Like Receptor 4
  • Viral Nonstructural Proteins