The B subunit of coagulation factor XIII is linked to renin and the Duffy blood group to alpha-spectrin on human chromosome 1

L R Griffiths; P G Board; M B Zwi; B J Morris; J G McLeod; G A Nicholson

doi:10.1159/000153843

The B subunit of coagulation factor XIII is linked to renin and the Duffy blood group to alpha-spectrin on human chromosome 1

Hum Hered. 1989;39(2):107-9. doi: 10.1159/000153843.

Authors

L R Griffiths¹, P G Board, M B Zwi, B J Morris, J G McLeod, G A Nicholson

Affiliation

¹ Department of Medicine, University of Sydney, Australia.

PMID: 2668157
DOI: 10.1159/000153843

Abstract

Family linkage studies were used to detect two linkage relationships on human chromosome 1. The B subunit of coagulation factor XIII showed significant linkage to renin with a maximum lod score of 5.071 at a distance of 10 cM. Significant linkage was also shown between the Duffy blood group and alpha-spectrin with linkage results giving a combined lod score of 3.194 at 5 cM.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Blood Group Antigens / genetics*
Chromosome Mapping
Chromosomes, Human, Pair 1*
Duffy Blood-Group System / genetics*
Factor XIII / genetics*
Genetic Linkage*
Genetic Markers
Humans
Recombination, Genetic
Renin / genetics*
Spectrin / genetics*

Substances

Blood Group Antigens
Duffy Blood-Group System
Genetic Markers
Spectrin
Factor XIII
Renin