Variations in Spike Glycoprotein Gene of MERS-CoV, South Korea, 2015

Emerg Infect Dis. 2016 Jan;22(1):100-4. doi: 10.3201/eid2201.151055.

Abstract

An outbreak of nosocomial infections with Middle East respiratory syndrome coronavirus occurred in South Korea in May 2015. Spike glycoprotein genes of virus strains from South Korea were closely related to those of strains from Riyadh, Saudi Arabia. However, virus strains from South Korea showed strain-specific variations.

Keywords: MERS-CoV; Middle East respiratory syndrome; Middle East respiratory syndrome coronavirus; South Korea; genetic evolution; outbreak; recombination; spike glycoprotein gene; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / genetics
  • Coronavirus Infections / virology
  • Cross Infection / epidemiology
  • Cross Infection / virology
  • Disease Outbreaks
  • Genetic Variation / genetics*
  • Humans
  • Male
  • Middle East Respiratory Syndrome Coronavirus / genetics*
  • Republic of Korea / epidemiology
  • Saudi Arabia / epidemiology
  • Spike Glycoprotein, Coronavirus / genetics*

Substances

  • Spike Glycoprotein, Coronavirus