PREDICT score and CYP2C19 polymorphism independently predict lack of efficacy of clopidogrel in cardiology patients

Clin Exp Pharmacol Physiol. 2016 Mar;43(3):379-81. doi: 10.1111/1440-1681.12531.

Authors

Affiliations

¹ Faculty of Pharmacy, University of Montenegro, Podgorica, Montenegro.
² Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
³ Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
⁴ High Medical School "Milutin Milanković", Belgrade, Serbia.
⁵ Public Health Institute, Kragujevac, Serbia.
⁶ Medical Center "Bežanijska kosa", Belgrade, Serbia.

PMID: 26699839
DOI: 10.1111/1440-1681.12531

No abstract available

Publication types

Clinical Trial
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Clopidogrel
Coronary Vessels / drug effects*
Cytochrome P-450 CYP2C19 / genetics*
Drug Resistance / genetics*
Humans
Multivariate Analysis
Platelet Aggregation / drug effects*
Platelet Aggregation / genetics
Polymorphism, Genetic*
Stents*
Ticlopidine / analogs & derivatives*
Ticlopidine / pharmacology

Substances

Clopidogrel
Cytochrome P-450 CYP2C19
Ticlopidine