Terminal or truncal ligation of the inferior thyroid artery during thyroidectomy? A prospective randomized trial

Int J Surg. 2016 Apr:28 Suppl 1:S13-6. doi: 10.1016/j.ijsu.2015.05.057. Epub 2015 Dec 18.

Abstract

Introduction: Thyroidectomy is a common procedure in general and endocrine surgery. The technique of ligation of inferior thyroid artery (ITA) has been invoked as a possible cause of appearance of postoperative hypocalcemia.

Methods: We performed a prospective randomized study involving 184 patients undergoing total thyroidectomy to evaluate the differences of truncal ligation versus distal ligation of ITA in terms of postoperative hypocalcemia, vocal fold palsy, voice and swallowing impairment. The patients were divided into group A (trunk ligation of ITA) and group B (terminal branches ligation of ITA).

Results: We evaluated postoperative PTH and calcemia (immediate, 6 and 12 months after thyroidectomy), postoperative day of discontinuation of calcium and vitamin D supplementation, voice and swallowing complaints, evaluated by mean of two specific tests available in literature, day of hospital discharge.

Conclusion: The only significant differences between the two groups were a higher immediate postoperative calcemia and a greater number of patients discharged without calcium and vitamin-D supplementation in the group B. In conclusion, no substantial differences were found between the two groups. The choice depends on the experience of the surgeon.

Keywords: Inferior thyroid artery; Multinodular goiter; Thyroidectomy.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Calcium / administration & dosage
  • Deglutition Disorders / etiology
  • Female
  • Hormone Replacement Therapy
  • Humans
  • Hypocalcemia / drug therapy
  • Hypocalcemia / etiology
  • Hypothyroidism / drug therapy
  • Hypothyroidism / etiology
  • Ligation
  • Male
  • Middle Aged
  • Prospective Studies
  • Thyroid Diseases / surgery*
  • Thyroid Gland / blood supply*
  • Thyroid Hormones / administration & dosage
  • Thyroid Nodule / surgery
  • Thyroidectomy / adverse effects*
  • Thyroidectomy / methods*
  • Treatment Outcome
  • Vitamin D / administration & dosage
  • Vocal Cord Paralysis / etiology

Substances

  • Thyroid Hormones
  • Vitamin D
  • Calcium