Significant reduction of central line-associated bloodstream infection rates in a tertiary neonatal unit

Dimitrios Rallis; Paraskevi Karagianni; Ifigeneia Papakotoula; Nikolaos Nikolaidis; Christos Tsakalidis

doi:10.1016/j.ajic.2015.10.040

Significant reduction of central line-associated bloodstream infection rates in a tertiary neonatal unit

Am J Infect Control. 2016 Apr 1;44(4):485-7. doi: 10.1016/j.ajic.2015.10.040. Epub 2015 Dec 21.

Authors

Dimitrios Rallis¹, Paraskevi Karagianni², Ifigeneia Papakotoula², Nikolaos Nikolaidis², Christos Tsakalidis²

Affiliations

¹ 2nd NICU and Neonatology Department, General Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: [email protected].
² 2nd NICU and Neonatology Department, General Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

PMID: 26717871
DOI: 10.1016/j.ajic.2015.10.040

Abstract

To evaluate the effectiveness of a quality initiative in reducing central line-associated bloodstream infections (CLABSIs) in our neonatal intensive care unit, we designed a prospective study (January 2012-September 2013) estimating CLABSI incidence before and after our implementation. CLABSI rates were significantly decreased after our intervention, from 12 cases per 1,000 central vascular catheter (CVC) days during the preinterventional period to 3.4 cases per 1,000 CVC days during the postinterventional period (P = .004).

Keywords: Central line–associated bloodstream infection; central vascular catheters; neonatal intensive care unit.

MeSH terms

Catheter-Related Infections / epidemiology*
Catheterization, Central Venous / adverse effects*
Female
Humans
Infant, Newborn
Intensive Care Units, Neonatal
Male
Prospective Studies
Sepsis / epidemiology*
Tertiary Care Centers