Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13)

Int J Lab Hematol. 2016 Apr;38(2):e15-8. doi: 10.1111/ijlh.12450. Epub 2016 Jan 5.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosomes, Human, Pair 12
  • Chromosomes, Human, Pair 4
  • ETS Translocation Variant 6 Protein
  • Gene Expression Regulation, Leukemic
  • Homeodomain Proteins / genetics*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Proto-Oncogene Proteins c-ets / genetics*
  • Receptor, Platelet-Derived Growth Factor alpha / genetics*
  • Repressor Proteins / genetics*
  • Transcriptional Activation*
  • Translocation, Genetic*

Substances

  • Gsx2 protein, human
  • Homeodomain Proteins
  • Proto-Oncogene Proteins c-ets
  • Repressor Proteins
  • Receptor, Platelet-Derived Growth Factor alpha