Objective: Bring a comprehensive overview of the available knowledge about thrombophilia in pregnat women.
Design: Overview study.
Setting: Departmentof Haematology and Transfusion Medicine, National Centre for Haemostasis and Thrombosis, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia.
Methods: Analysis of literary sources.
Conclusion: Anticoagulation may provide benefit for women both as prophylaxis and as treatment for venous thrombosis during pregnancy. The use of anticoagulants in women with inherited thrombophilia and history of miscarriage remains controversial. In contrast, pregnant women with acquired thrombophilia should be anticoagulated.
Keywords: complications.; pregnacy; trombophilia.