Abstract
Meropenem-susceptible and -resistant Aeromonas dhakensis isolates from blood cultures of a fatal case of septicemia were analyzed. The two isolates were homologous and gene expression of metallo-β-lactamase in the resistant strain was upregulated. Physicians should be aware of the possibility of the induction of carbapenem-resistance, following the use of carbapenems in the treatment of Aeromonas infection.
MeSH terms
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Adolescent
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Aeromonas / drug effects*
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Aeromonas / isolation & purification
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / pharmacology*
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Bacteremia / microbiology*
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Blood / microbiology*
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Female
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Gene Expression Profiling
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Gram-Negative Bacterial Infections / microbiology*
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Humans
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Male
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Meropenem
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Middle Aged
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Thienamycins / pharmacology*
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Time Factors
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Up-Regulation
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beta-Lactam Resistance*
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beta-Lactamases / biosynthesis
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beta-Lactamases / genetics
Substances
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Anti-Bacterial Agents
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Thienamycins
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beta-Lactamases
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Meropenem