Epidemiological Study of Thyroid Pathology in a University Hospital

Acta Chir Belg. 2015 Nov-Dec;115(6):414-7. doi: 10.1080/00015458.2015.11681143.

Abstract

Objectives: The incidence of papillary thyroid carcinoma increased in several countries. The purpose of this study was to quantify the changes in thyroid carcinomas in our University Hospital.

Study design: Retrospective study.

Methods: All 1.927 thyroidectomy cases studied in the Pathology Department of Hotel-Dieu de France Hospital (Beirut, Lebanon), between 2003 and 2013, were included.

Results: The Female/Male Sex Ratio of the studied population was 3.7/1. The mean age of female patients was significantly lower than that of male patients. The most frequent diagnoses were multinodular goiter (78%) and papillary-carcinoma (26%). 337 cases had a single lesion on gross examination. 21 of them were diagnosed with follicular carcinoma and 59 with follicular adenoma. A statistically significant correlation was found between the unicity of the lesion on gross examination and the final diagnosis of a follicular neoplasm. Thyroid carcinoma was multifocal in 33% of the cases and bilateral in 24%. A statistically significant increase in thyroid carcinoma proportion (from 15% in 2003 to 44% in 2013) was found. Among all thyroid carcinomas, the proportion of papillary type increased from 65% in 2003 to 94% in 2013 ; this increase remained statistically significant after the exclusion of papillary micro-carcinomas, whose proportion was stable throughout the 11 years.

Conclusions: In this study, we noted a statistically significant increase in the frequency of thyroid carcinoma, especially of the papillary type. The unicity of the lesion on gross examination is significantly associated with a follicular neoplasm.

MeSH terms

  • Adenoma / epidemiology*
  • Adenoma / pathology
  • Adenoma / surgery
  • Adult
  • Carcinoma / epidemiology*
  • Carcinoma / pathology
  • Carcinoma / surgery
  • Carcinoma, Papillary
  • Female
  • Goiter, Nodular / epidemiology*
  • Goiter, Nodular / pathology
  • Goiter, Nodular / surgery
  • Hospitals, University
  • Humans
  • Lebanon
  • Male
  • Middle Aged
  • Retrospective Studies
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / epidemiology*
  • Thyroid Neoplasms / pathology
  • Thyroid Neoplasms / surgery
  • Thyroidectomy
  • Thyroiditis / epidemiology*
  • Thyroiditis / pathology
  • Thyroiditis / surgery