Diagnosis of an additional in situ melanoma does not influence survival for patients with a single invasive melanoma: A registry-based follow-up study

Australas J Dermatol. 2016 Feb;57(1):57-60. doi: 10.1111/ajd.12429. Epub 2016 Jan 18.

Abstract

Using a large (N= 25 493) population-based cohort from Queensland, Australia, we compared melanoma survival among cases with a single invasive melanoma only against those who also had a diagnosis of a single in situ melanoma. After adjustment for sex, age, body site, clinicopathological subtype, thickness and ulceration, it was found that there was no difference (P = 0.99) in 10-year melanoma-specific mortality following a diagnosis of an invasive lesion, whether or not an in situ melanoma was also present. We conclude that in situ melanomas do not alter the prognosis of an invasive melanoma.

Keywords: in situ; invasive; melanoma; survival.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Melanoma / mortality*
  • Melanoma / pathology*
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasms, Second Primary / mortality*
  • Neoplasms, Second Primary / pathology*
  • Queensland / epidemiology
  • Registries
  • Skin Neoplasms / mortality*
  • Skin Neoplasms / pathology*
  • Survival Rate
  • Young Adult