Expression of the RESA gene in Plasmodium falciparum isolate FCR3 is prevented by a subtelomeric deletion

Mol Cell Biol. 1989 Aug;9(8):3584-7. doi: 10.1128/mcb.9.8.3584-3587.1989.

Abstract

We show here that the Plasmodium falciparum isolate FCR3 does not express the ring-infected erythrocyte surface antigen (RESA). This is because the 5' end of the RESA gene has been inverted and partly deleted and a telomere has been added to it. We propose a model to explain these events.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Antigens, Protozoan / genetics*
  • Antigens, Surface / genetics*
  • Antigens, Surface / immunology
  • Base Sequence
  • Chromosome Deletion
  • Chromosome Inversion
  • Chromosome Mapping
  • Gene Amplification
  • Immunoblotting
  • Molecular Sequence Data
  • Mutation
  • Plasmodium falciparum / genetics*
  • Plasmodium falciparum / immunology
  • Protozoan Proteins*

Substances

  • Antigens, Protozoan
  • Antigens, Surface
  • Protozoan Proteins
  • ring-infected erythrocyte surface antigen (RESA), Plasmodium falciparum

Associated data

  • GENBANK/M28195