Bisphosphonate-related osteonecrosis of the jaws: Report of a case using conservative protocol

Spec Care Dentist. 2016 Jan;36(1):43-7. doi: 10.1111/scd.12143. Epub 2015 Nov 24.

Abstract

Bisphosphonates have been the first-line treatment option for osteometabolic diseases, such as osteoporosis, hypercalcaemia in malignant bone diseases, and in bone metastasis. It is possible to observe a growing number of cases of osteonecrosis of the jaws in patients using this medication, called bisphosphonate-related osteonecrosis of the jaws. The purpose of this study was to report a conservative treatment for bisphosphonate-related osteonecrosis of the jaws--Stage 2, using antibacterial solution and low-level laser therapy. At the end of the treatment, the patient presented improvement of the lesion with the healing of the mucosa. The literature still lacks successful definite protocols, thus the present case may contribute with another option for conservative management for bisphosphonate-related osteonecrosis of the jaws. More research is necessary in order to develop a good protocol management for bisphosphonate-related osteonecrosis of the jaws.

Keywords: bisphosphonates; iodides and hydrogen peroxide; low-level laser therapy; osteonecrosis.

Publication types

  • Case Reports

MeSH terms

  • Bisphosphonate-Associated Osteonecrosis of the Jaw / diagnosis*
  • Bisphosphonate-Associated Osteonecrosis of the Jaw / therapy*
  • Combined Modality Therapy
  • Female
  • Humans
  • Middle Aged