The effect of a damaged skin barrier on percutaneous absorption of SDS and skin hydration investigated by confocal Raman spectroscopy

Exp Dermatol. 2016 May;25(5):390-2. doi: 10.1111/exd.12950. Epub 2016 Mar 8.

Authors

Magdalena Hoppel¹, Kristina Kwizda², Dieter Baurecht³, Manuel Caneri², Claudia Valenta^{1

2}

Affiliations

¹ Research Platform 'Characterisation of Drug Delivery Systems on Skin and Investigations of Involved Mechanisms', University of Vienna, Vienna, Austria.
² Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Vienna, Austria.
³ Department of Physical Chemistry, University of Vienna, Vienna, Austria.

PMID: 26782647
DOI: 10.1111/exd.12950

No abstract available

Keywords: Confocal Raman spectroscopy; SDS; damaged skin barrier; skin hydration; tape stripping.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Skin / chemistry
Skin / drug effects*
Skin / metabolism
Skin Absorption*
Sodium Dodecyl Sulfate / adverse effects*
Sodium Dodecyl Sulfate / metabolism
Spectrum Analysis, Raman*
Swine

Substances

Sodium Dodecyl Sulfate