Abstract
Efficiency of ionic liquid supported organotin reagents in halodemetalation reaction has been investigated. High radiochemical yields of astatinated and iodinated compounds have been obtained using simple work-up procedure. This methodology represents a straightforward approach for the preparation of molecular imaging and therapy agents in nuclear medicine.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Iodine Radioisotopes / chemistry
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Iodine Radioisotopes / therapeutic use
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Ionic Liquids / chemistry*
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Molecular Imaging / methods*
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Molecular Structure
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Nuclear Medicine
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Organotin Compounds / chemistry*
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Radioimmunoassay
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Radiopharmaceuticals / chemical synthesis
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Radiopharmaceuticals / chemistry
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Radiopharmaceuticals / therapeutic use*
Substances
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Iodine Radioisotopes
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Ionic Liquids
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Organotin Compounds
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Radiopharmaceuticals