Regorafenib-induced hand-foot skin reaction with striking epidermal dysmaturation - a new histopathological pattern associated with the use of multi-kinase inhibitors

Br J Dermatol. 2016 Jul;175(1):216-7. doi: 10.1111/bjd.14417. Epub 2016 Apr 19.

Authors

M Llamas-Velasco^{1

2}, I Hegyi¹, U Hesterberg³, E Daudén², L Requena⁴, W Kempf¹

Affiliations

¹ Kempf und Pfaltz Histologische Diagnostik, Seminarstrasse 1, CH-8042, Zürich, Switzerland.
² Hospital de La Princesa, Madrid, Spain.
³ Dermatology Practice, Berne, Switzerland.
⁴ Fundación Jiménez Díaz, Madrid, Spain.

PMID: 26801207
DOI: 10.1111/bjd.14417

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Drug Eruptions / etiology*
Epidermis / drug effects*
Foot Dermatoses / etiology*
Hand Dermatoses / etiology*
Humans
Male
Middle Aged
Phenylurea Compounds / adverse effects*
Protein Kinase Inhibitors / adverse effects*
Pyridines / adverse effects*

Substances

Phenylurea Compounds
Protein Kinase Inhibitors
Pyridines
regorafenib