Catheter ablation for atrioventricular nodal reentrant tachycardia in patients with congenital heart disease

Heart Rhythm. 2016 Jun;13(6):1228-37. doi: 10.1016/j.hrthm.2016.01.020. Epub 2016 Jan 21.

Abstract

Background: Variability in atrioventricular (AV) node location in congenital heart disease (CHD) can make catheter ablation for atrioventricular nodal reentrant tachycardia (AVNRT) challenging.

Objective: The purpose of this study was to describe institutional technique and outcomes for slow pathway modification in a cohort with CHD.

Methods: The study consisted of a retrospective review of CHD patients who underwent study from 2001 to 2013 with a diagnosis of AVNRT. Outcomes for slow pathway modification were recorded. In cases in which ablation was deferred, the reasons for this choice were examined.

Results: Forty-nine patients (median age 19 years) were included. CHD anatomy involved d-transposition of the great arteries (n = 6), "congenitally corrected" transposition of the great arteries (n = 4), Ebstein anomaly (n = 4), tetralogy of Fallot (n = 5), venous anomalies (n = 8), single ventricle (n = 16), and miscellaneous (n = 6). Ablation was attempted in 39 patients, using radiofrequency energy in 24, cryoablation in 8, and both in 7. Acute success rate was 92% (36/39). One patient had first-degree block in response to cryoablation, but no other complications occurred. At median follow-up 32 months, 1 patient had AVNRT recurrence. Most of the 10 patients in whom ablation was deferred had single-ventricle anatomy with uncertain AV node location.

Conclusion: Ablation for AVNRT in CHD can be accomplished successfully with attention to underlying anatomy and prior surgery. Patients with single ventricle are a difficult subgroup, and a pharmacologic approach may be indicated in some cases if node localization is ambiguous.

Keywords: Atrioventricular nodal reentrant tachycardia; Catheter ablation; Conduction system anatomy; Congenital heart disease; Supraventricular tachycardia.

MeSH terms

  • Adolescent
  • Adult
  • Atrioventricular Node* / pathology
  • Atrioventricular Node* / physiopathology
  • Catheter Ablation / methods
  • Child, Preschool
  • Electrocardiography / methods
  • Electrophysiologic Techniques, Cardiac / methods
  • Female
  • Follow-Up Studies
  • Heart Conduction System / pathology
  • Heart Conduction System / physiopathology
  • Heart Defects, Congenital* / complications
  • Heart Defects, Congenital* / diagnosis
  • Heart Defects, Congenital* / physiopathology
  • Humans
  • Male
  • Massachusetts
  • Middle Aged
  • Outcome Assessment, Health Care
  • Recurrence
  • Tachycardia, Atrioventricular Nodal Reentry* / diagnosis
  • Tachycardia, Atrioventricular Nodal Reentry* / etiology
  • Tachycardia, Atrioventricular Nodal Reentry* / surgery
  • Time Factors