A novel HLA-DRB1 allele, DRB1*15:66:02 was identified in a Chinese potential donor by sequence-based typing

HLA. 2016 Jan;87(1):61-3. doi: 10.1111/tan.12722.

Abstract

DRB1*15:66:02 differs from DRB1*15:66:01 at codons 57 and 58 resulting in no coding change.

Keywords: DRB1*15:66:02; human leukocyte antigen; novel allele; sequence-based typing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Asian People
  • Base Sequence
  • Codon
  • Exons
  • Gene Expression
  • Genetic Loci
  • HLA-DRB1 Chains / genetics*
  • HLA-DRB1 Chains / immunology
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells / cytology
  • Hematopoietic Stem Cells / immunology*
  • Histocompatibility Testing
  • Humans
  • Molecular Sequence Data
  • Polymorphism, Single Nucleotide*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Silent Mutation*
  • Tissue Donors

Substances

  • Codon
  • HLA-DRB1 Chains