[PROTEIN CONTENT CHANGES IN RATS' LIVER AND BRAIN UNDER CHRONIC ALCOHOL INTOXICATION]

Lik Sprava. 2015 Apr-Jun:(3-4):153-9.
[Article in Ukrainian]

Abstract

An electrophoretic investigation of quantitative protein content in rat's' tissyes under chronic alcoholic intoxication has been done. It was shown the significant increase of protein content with molecular mass 55, 48-50, 43-45, 39-41 KDa and the decrease-of protein fractions with molecular mass 46-48, 34-35, 27-30, 16-18 KDa accordingly in liver and brain homogenates of experimental animals.

Publication types

  • English Abstract

MeSH terms

  • Alcoholism / metabolism*
  • Alcoholism / physiopathology
  • Animals
  • Animals, Outbred Strains
  • Brain / drug effects*
  • Brain / metabolism
  • Brain Chemistry
  • Electrophoresis, Polyacrylamide Gel
  • Ethanol / toxicity*
  • Female
  • Liver / chemistry
  • Liver / drug effects*
  • Liver / metabolism
  • Molecular Weight
  • Nerve Tissue Proteins / isolation & purification
  • Nerve Tissue Proteins / metabolism*
  • Rats

Substances

  • Nerve Tissue Proteins
  • Ethanol