Isolated Hepatitis B Core Antibody is Associated With Advanced Hepatic Fibrosis in HIV/HCV Infection But Not in HIV Infection Alone

J Acquir Immune Defic Syndr. 2016 May 1;72(1):e14-7. doi: 10.1097/QAI.0000000000000941.

Abstract

HIV+/HCV+ persons with isolated HBcAb have a higher prevalence of advanced fibrosis than persons who are non-immune to HBV, who have resolved HBV, or who are HbsAb+ only.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Aspartate Aminotransferases / blood
  • CD4 Lymphocyte Count
  • Coinfection / virology
  • Cross-Sectional Studies
  • Female
  • HIV Infections / complications
  • HIV Infections / immunology*
  • Hepatitis B Antibodies / blood
  • Hepatitis B Antibodies / immunology*
  • Hepatitis B Core Antigens / immunology*
  • Hepatitis B Surface Antigens / immunology*
  • Hepatitis B virus / immunology
  • Hepatitis C / complications
  • Hepatitis C / immunology*
  • Humans
  • Liver Cirrhosis / immunology*
  • Liver Cirrhosis / virology
  • Male
  • Middle Aged
  • Platelet Count
  • Veterans
  • Viremia / immunology
  • Viremia / virology

Substances

  • Hepatitis B Antibodies
  • Hepatitis B Core Antigens
  • Hepatitis B Surface Antigens
  • Aspartate Aminotransferases