Surgical Treatment of Renal Cell Carcinoma With Cavoatrial Involvement: A Systematic Review of the Literature

Ann Thorac Surg. 2016 Mar;101(3):1213-21. doi: 10.1016/j.athoracsur.2015.10.003. Epub 2016 Jan 29.

Abstract

The treatment of renal cell carcinoma (RCC) with cavoatrial involvement represents a major surgical challenge. To date, many surgical strategies have been proposed. However, general agreement on the best approach does not yet exist. Deep hypothermic circulatory arrest (DHCA) is the most commonly used method and allows complete tumor resection without increasing operative risk. Cardiopulmonary bypass (CPB) without circulatory arrest and methods using no CBP were also proposed, without a clear evidence of superiority of 1 technique over the others. Further studies are needed to evaluate the possible role of alternative techniques compared with deep hypothermic circulatory arrest.

Publication types

  • Comparative Study
  • Review
  • Systematic Review

MeSH terms

  • Carcinoma, Renal Cell / mortality
  • Carcinoma, Renal Cell / pathology
  • Carcinoma, Renal Cell / surgery*
  • Cardiopulmonary Bypass / methods*
  • Circulatory Arrest, Deep Hypothermia Induced / methods*
  • Circulatory Arrest, Deep Hypothermia Induced / mortality
  • Female
  • Heart Atria / pathology
  • Heart Atria / surgery
  • Hospital Mortality
  • Humans
  • Kidney Neoplasms / mortality
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / surgery*
  • Male
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Neoplastic Cells, Circulating / pathology*
  • Nephrectomy / methods
  • Prognosis
  • Risk Assessment
  • Survival Analysis
  • Thrombectomy / methods
  • Vena Cava, Inferior / pathology
  • Vena Cava, Inferior / surgery