Racial/Ethnic Differences in the Association Between Hospitalization and Kidney Transplantation Among Waitlisted End-Stage Renal Disease Patients

Transplantation. 2016 Dec;100(12):2735-2745. doi: 10.1097/TP.0000000000001072.

Abstract

Background: Even after placement on the deceased donor waitlist, there are racial disparities in access to kidney transplant. The association between hospitalization, a proxy for health while waitlisted, and disparities in kidney transplant has not been investigated.

Methods: We used United States Renal Data System Medicare-linked data on waitlisted end-stage renal disease patients between 2005 and 2009 with continuous enrollment in Medicare Parts A & B (n = 24 581) to examine the association between annual hospitalization rate and odds of receiving a deceased donor kidney transplant. We used multilevel mixed effects models to estimate adjusted odds ratios, controlling for individual-, transplant center-, and organ procurement organization-level clustering.

Results: Blacks and Hispanics were more likely than whites to be hospitalized for circulatory system or endocrine, nutritional, and metabolic diseases (P < 0.001). After adjustment, compared with individuals not hospitalized, patients who were hospitalized frequently while waitlisted were less likely to be transplanted (>2 vs 0 hospitalizations/year adjusted odds ratios = 0.57; P < 0.001). Though blacks and Hispanics were more likely to be hospitalized than whites (P < 0.001), adjusting for hospitalization did not change estimated racial/ethnic disparities in kidney transplantation.

Conclusions: Individuals hospitalized while waitlisted were less likely to receive a transplant. However, hospitalization does not account for the racial disparity in kidney transplantation after waitlisting.

MeSH terms

  • Adult
  • Aged
  • Black People
  • Black or African American
  • Cluster Analysis
  • Female
  • Healthcare Disparities*
  • Hispanic or Latino
  • Hospitalization*
  • Humans
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / statistics & numerical data*
  • Living Donors
  • Male
  • Medicare
  • Middle Aged
  • Multivariate Analysis
  • Odds Ratio
  • Renal Insufficiency / surgery*
  • Tissue Donors
  • Tissue and Organ Procurement / methods
  • United States
  • Waiting Lists*
  • White People