Excellent outcome with a high proportion of mixed chimerism in patients with severe aplastic anemia treated with partially T-cell-depleted peripheral hematopoietic stem cell transplants

Bone Marrow Transplant. 2016 Jun;51(6):860-2. doi: 10.1038/bmt.2015.356. Epub 2016 Feb 8.

Authors

S Masouridi-Levrat¹, F Simonetta¹, Y Beauverd¹, O Tsopra¹, Y Tirefort¹, C Stephan¹, E Levrat², M Ansari¹, F Verholen³, E Roosnek¹, J R Passweg⁴, Y Chalandon¹

Affiliations

¹ Stem Cell and Bone Marrow Transplant Centre, Division of Hematology, Geneva's University Hospitals and University of Geneva Faculty of Medicine, Geneva, Switzerland.
² Department of Hemato-oncology, Hôpital Fribourgeois, Fribourg, Switzerland.
³ Sanofi-Aventis, Vernier, Switzerland.
⁴ Division of Hematology, Basel University Hospital, Basel, Switzerland.

PMID: 26855156
DOI: 10.1038/bmt.2015.356

No abstract available

MeSH terms

Adolescent
Adult
Anemia, Aplastic / therapy*
Antigens, CD34 / metabolism
Female
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells / cytology
Humans
Male
Middle Aged
Peripheral Blood Stem Cell Transplantation / methods*
Retrospective Studies
T-Lymphocytes / cytology*
Time Factors
Transplantation Chimera*
Transplantation, Homologous
Treatment Outcome
Young Adult

Substances

Antigens, CD34