Identification of MYC mutations in acute myeloid leukemias with NUP98-NSD1 translocations

Leukemia. 2016 Jul;30(7):1621-4. doi: 10.1038/leu.2016.19. Epub 2016 Feb 9.

Authors

V-P Lavallée^{1

2}, S Lemieux^{1

3}, G Boucher¹, P Gendron¹, I Boivin¹, S Girard¹, J Hébert^{1

2

4

5}, G Sauvageau^{1

2

4

5}

Affiliations

¹ The Leucegene Project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada.
² Division of Hematology, Maisonneuve-Rosemont Hospital, Montréal, Québec, Canada.
³ Department of Computer Science and Operations Research, Université de Montréal, Montréal, Québec, Canada.
⁴ Quebec Leukemia Cell Bank, Maisonneuve-Rosemont Hospital, Montréal, Québec, Canada.
⁵ Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada.

PMID: 26859078
DOI: 10.1038/leu.2016.19

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
DNA Mutational Analysis
Humans
Leukemia, Myeloid, Acute / genetics*
Middle Aged
Mutation
Oncogene Proteins, Fusion / genetics*
Proto-Oncogene Proteins c-myc / genetics*
Transcriptome
Translocation, Genetic
Young Adult

Substances

MYC protein, human
NUP98-NSD1 protein, human
Oncogene Proteins, Fusion
Proto-Oncogene Proteins c-myc