Alveolar soft-part sarcoma in the left forearm with cardiac metastasis: A case report and literature review

Oncol Lett. 2016 Jan;11(1):81-84. doi: 10.3892/ol.2015.3889. Epub 2015 Nov 6.

Abstract

Alveolar soft-part sarcoma (ASPS) is an uncommon soft-tissue neoplasm, which is commonly found in the deep soft tissues of the extremities, with a propensity for recurrence and metastasis. However, the metastasis of ASPS to the heart is exceedingly rare. The present study reports such a rare case with cardiac metastasis. Using computed tomography, a 37-year-old man was diagnosed with brain, lung and spleen metastases from a previously treated ASPS in the left forearm. Cardiac metastasis was then diagnosed 1 month later. Despite chemotherapy and palliative whole-brain radiotherapy, the patient succumbed to the disease shortly after. This case suggests that the widespread metastases and cardiac involvement of ASPS may result in a poor outcome.

Keywords: alveolar soft-part sarcoma; cardiac metastasis; chemotherapy; multiple metastases.