Improved visualisation of real-time recordings during third generation cryoballoon ablation: a comparison between the novel short-tip and the second generation device

J Interv Card Electrophysiol. 2016 Sep;46(3):307-14. doi: 10.1007/s10840-016-0114-9. Epub 2016 Feb 12.

Abstract

Background: The third-generation Cryoballoon Advance Short-tip (CB-ST) has been designed with a 40 % shortened tip length compared with the former second generation CB advance device (CB-A). Ideally, a shorter tip should permit an improved visualisation of real-time recordings in the pulmonary vein (PV) due to a more proximal positioning of the inner lumen mapping catheter. We sought to compare the incidence of visualisation of real-time recordings in patients having undergone ablation with the CB-ST with patients having received CB-A ablation.

Methods: All patients having undergone CB ablation using CB-ST technology and the last 500 consecutive patients having undergone CB-A ablation were analysed. Exclusion criteria were the presence of an intracavitary thrombus, uncontrolled heart failure, moderate or severe valvular disease, and contraindications to general anaesthesia.

Results: A total of 600 consecutive patients (58.1 ± 12.9 years, 64 % males) were evaluated (100 CB-ST and 500 CB-A ablations). Real-time recordings were significantly more prevalent in the CB-ST population compared with CB-A group (85.7 vs 67.2 %, p < 0.0001). Real-time recordings could be more frequently visualised in the CB-ST group in all types of veins (LSPV 89 vs 73.4 %, p = 0.0005; LIPV 84 vs 65.6 %, p = 0.0002; RSPV 87 vs 67.4 %, p < 0.0001; RIPV 83 vs 62.4 %, p < 0.0001).

Conclusion: The rate of visualisation of real-time recordings is significantly higher during third-generation CB-ST ablation if compared to the second-generation CB-A device. Real-time recordings can be visualised in approximately 85.7 % of veins with this novel cryoballoon.

Keywords: Atrial fibrillation; Catheter ablation; Cryoballoon; Pulmonary vein isolation; Short tip.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Aged
  • Atrial Fibrillation / diagnosis*
  • Atrial Fibrillation / surgery*
  • Body Surface Potential Mapping / instrumentation*
  • Body Surface Potential Mapping / methods
  • Catheter Ablation / instrumentation*
  • Catheter Ablation / methods
  • Computer Systems
  • Cryosurgery / instrumentation*
  • Cryosurgery / methods
  • Equipment Design
  • Equipment Failure Analysis
  • Female
  • Humans
  • Image Enhancement / instrumentation
  • Male
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Surgery, Computer-Assisted / instrumentation*
  • Surgery, Computer-Assisted / methods
  • Treatment Outcome
  • User-Computer Interface