Patient knowledge and information-seeking about personalized cancer therapy

Int J Med Inform. 2016 Apr:88:52-7. doi: 10.1016/j.ijmedinf.2016.01.005. Epub 2016 Jan 18.

Abstract

Background: Understanding patients' knowledge and prior information-seeking regarding personalized cancer therapy (PCT) may inform future patient information systems, consent for molecular testing and PCT protocols. We evaluated breast cancer patients' knowledge and information-seeking behaviors regarding PCT.

Methods: Newly registered female breast cancer patients (n=100) at a comprehensive cancer center completed a self-administered questionnaire prior to their first clinic visit.

Results: Knowledge regarding cancer genetics and PCT was moderate (mean 8.7±3.8 questions correct out of 16). A minority of patients (27%) indicated that they had sought information regarding PCT. Higher education (p=0.009) and income levels (p=0.04) were associated with higher knowledge scores and with seeking PCT information (p=0.04). Knowledge was not associated with willingness to participate in PCT research.

Conclusion: Educational background and financial status impact patient knowledge as well as information-seeking behavior. For most patients, clinicians are likely to be patients' initial source of information about PCT. Understanding patients' knowledge deficits at presentation may help inform patient education efforts.

Keywords: Information-seeking behavior; Molecular testing; Patient attitudes; Patient knowledge; Personalized cancer therapy.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / psychology*
  • Breast Neoplasms / therapy*
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Information Seeking Behavior*
  • Middle Aged
  • Patient Participation / statistics & numerical data*
  • Precision Medicine / psychology*
  • Young Adult