Development of recombinant hirudin as a therapeutic anticoagulant and antithrombotic agent: some objective considerations

Semin Thromb Hemost. 1989 Jul;15(3):316-33. doi: 10.1055/s-2007-1002724.
No abstract available

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Blood Coagulation / drug effects
  • Blood Coagulation Tests
  • Hemorrhage / chemically induced
  • Hirudin Therapy*
  • Hirudins / pharmacokinetics
  • Hirudins / pharmacology
  • Hirudins / toxicity
  • Recombinant Proteins / pharmacokinetics
  • Recombinant Proteins / pharmacology
  • Recombinant Proteins / therapeutic use*
  • Recombinant Proteins / toxicity
  • Thrombin / antagonists & inhibitors
  • Thrombosis / prevention & control*

Substances

  • Hirudins
  • Recombinant Proteins
  • Thrombin