RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8

J Allergy Clin Immunol. 2016 Jul;138(1):289-292.e6. doi: 10.1016/j.jaci.2015.11.033. Epub 2016 Feb 13.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Base Sequence
  • CD4-Positive T-Lymphocytes / immunology
  • CD4-Positive T-Lymphocytes / pathology
  • CD8-Positive T-Lymphocytes / immunology
  • CD8-Positive T-Lymphocytes / pathology
  • Child
  • Chromosomes, Human, Pair 9 / chemistry*
  • Consanguinity
  • Exome Sequencing
  • Exons
  • Female
  • Guanine Nucleotide Exchange Factors / genetics*
  • Guanine Nucleotide Exchange Factors / immunology
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Immunologic Deficiency Syndromes / diagnosis
  • Immunologic Deficiency Syndromes / genetics*
  • Immunologic Deficiency Syndromes / immunology
  • Immunologic Deficiency Syndromes / pathology
  • Lymphocyte Count
  • Male
  • Mutagenesis, Insertional*
  • Pedigree
  • Primary Immunodeficiency Diseases
  • Siblings

Substances

  • DOCK8 protein, human
  • Guanine Nucleotide Exchange Factors

Supplementary concepts

  • T cell immunodeficiency primary