Geometrical deployment for braided stent

Med Image Anal. 2016 May:30:85-94. doi: 10.1016/j.media.2016.01.006. Epub 2016 Jan 30.

Abstract

The prediction of flow diverter stent (FDS) implantation for the treatment of intracranial aneurysms (IAs) is being increasingly required for hemodynamic simulations and procedural planning. In this paper, a deployment model was developed based on geometrical properties of braided stents. The proposed mathematical description is first applied on idealized toroidal vessels demonstrating the stent shortening in curved vessels. It is subsequently generalized to patient specific vasculature predicting the position of the filaments along with the length and local porosity of the stent. In parallel, in-vitro and in-vivo FDS deployments were measured by contrast-enhanced cone beam CT (CBCT) in idealized and patient-specific geometries. These measurements showed a very good qualitative and quantitative agreement with the virtual deployments and provided experimental validations of the underlying geometrical assumptions. In particular, they highlighted the importance of the stent radius assessment in the accuracy of the deployment prediction. Thanks to its low computational cost, the proposed model is potentially implementable in clinical practice providing critical information for patient safety and treatment outcome assessment.

Keywords: Braided stent; Flow diverter stent; Geometrical model; Intracranial aneurysm; Virtual deployment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Angiography / methods
  • Computer Simulation
  • Computer-Aided Design
  • Equipment Failure Analysis
  • Humans
  • Intracranial Aneurysm / diagnostic imaging*
  • Intracranial Aneurysm / pathology
  • Intracranial Aneurysm / surgery*
  • Models, Cardiovascular*
  • Prosthesis Design
  • Prosthesis Implantation / methods*
  • Stents*
  • Surgery, Computer-Assisted / methods*
  • Treatment Outcome