Prehospital CPAP Therapy by Emergency Physicians in Patients with Acute Respiratory Failure due to Acute Cardiogenic Pulmonary Edema or Acutely Exacerbated COPD

In Vivo. 2016 Mar-Apr;30(2):133-9.

Abstract

Background: Acute respiratory failure is a frequent cause of emergency medical missions. Continuous positive airway pressure (CPAP) therapy could be particularly beneficial, avoiding risks associated with intubation and invasive ventilation. Hardly any data exist from Germany on this matter.

Patients and methods: CPAP therapy with the Boussignac system as additional measure was introduced in cases of acute cardiogenic pulmonary edema (ACPE) or decompensated chronic obstructive pulmonary disease (COPD) in a physician-supported emergency medical services system (EMS).

Results: A total of 57 patients, 35 with ACPE and 22 with COPD, received CPAP. Oxygen saturation improved from 81.6% to 94.8%, and respiration rate from 26.9/min to 18.9/min (p<0.001). Seven patients (12.2%) needed secondary intubation [COPD: one patient; ACPE: six patients, including three with acute coronary syndrome (ACS)].

Conclusion: In physician-supported EMS, CPAP using the Boussignac system is an effective additional measure for ACPE or COPD. For causal ACS, the risk of therapy failure increases.

Keywords: Boussignac; COPD; CPAP; Continuous positive airway pressure; cardiogenic pulmonary edema; chronic obstructive pulmonary disease; emergency medical services.

MeSH terms

  • Acute Disease
  • Aged
  • Aged, 80 and over
  • Continuous Positive Airway Pressure* / methods
  • Disease Progression
  • Emergency Medical Services*
  • Female
  • Humans
  • Male
  • Pulmonary Disease, Chronic Obstructive / complications*
  • Pulmonary Edema / complications*
  • Respiratory Insufficiency / etiology*
  • Respiratory Insufficiency / therapy*
  • Treatment Outcome