The prophylactic activity of amoxycillin/clavulanate and cefoxitin in vascular surgery--a randomized clinical study

H J Dieterich; J Groh; K Behringer; L Lauterjung; E Martin

doi:10.1093/jac/24.suppl_b.209

The prophylactic activity of amoxycillin/clavulanate and cefoxitin in vascular surgery--a randomized clinical study

J Antimicrob Chemother. 1989 Nov:24 Suppl B:209-11. doi: 10.1093/jac/24.suppl_b.209.

Authors

H J Dieterich¹, J Groh, K Behringer, L Lauterjung, E Martin

Affiliation

¹ Institute of Anaesthesiology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, FRG.

PMID: 2691482
DOI: 10.1093/jac/24.suppl_b.209

Abstract

In a randomized clinical study, 141 patients who had to undergo operations on the aorta or the main arteries received either amoxycillin/clavulanate or cefoxitin perioperatively for prophylaxis. As no wound infection occurred amoxycillin/clavulanate and cefoxitin were found to be equal in effectiveness.

Publication types

Clinical Trial
Comparative Study
Randomized Controlled Trial

MeSH terms

Adult
Aged
Aged, 80 and over
Amoxicillin / therapeutic use*
Amoxicillin-Potassium Clavulanate Combination
Cefoxitin / therapeutic use*
Clavulanic Acids / therapeutic use*
Drug Therapy, Combination / therapeutic use
Female
Humans
Male
Middle Aged
Randomized Controlled Trials as Topic
Surgical Wound Infection / microbiology
Surgical Wound Infection / prevention & control*
Vascular Surgical Procedures*

Substances

Clavulanic Acids
Cefoxitin
Amoxicillin-Potassium Clavulanate Combination
Amoxicillin