Abstract
Depression, anxiety and psychomotor performance were assessed in 20 depressed patients during double-blind treatment with amitriptyline or trazodone. There was no difference in onset of antidepressant or anxiolytic action. No decrement or improvement on computerised tasks was found. Dry mouth was significantly more frequent and severe with amitriptyline.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Adult
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Aged
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Amitriptyline / therapeutic use*
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Depressive Disorder / drug therapy*
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Depressive Disorder / psychology
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Double-Blind Method
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Female
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Humans
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Male
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Middle Aged
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Problem Solving / drug effects*
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Psychiatric Status Rating Scales
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Psychomotor Performance / drug effects*
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Randomized Controlled Trials as Topic
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Reaction Time / drug effects*
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Trazodone / therapeutic use*