Cytolytic hepatitis related to simeprevir overdose in a patient with cirrhosis and HIV-HCV genotype 1 coinfection

Eur J Gastroenterol Hepatol. 2016 Apr;28(4):486-7. doi: 10.1097/MEG.0000000000000508.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antiviral Agents / administration & dosage
  • Antiviral Agents / adverse effects*
  • Chemical and Drug Induced Liver Injury / diagnosis
  • Chemical and Drug Induced Liver Injury / etiology*
  • Coinfection*
  • Drug Overdose
  • Drug Substitution
  • Drug Therapy, Combination
  • Genotype
  • HIV Infections / complications*
  • HIV Infections / diagnosis
  • Hepacivirus / drug effects*
  • Hepacivirus / genetics
  • Hepacivirus / pathogenicity
  • Hepatitis C, Chronic / complications
  • Hepatitis C, Chronic / diagnosis
  • Hepatitis C, Chronic / drug therapy*
  • Humans
  • Liver Cirrhosis / diagnosis
  • Liver Cirrhosis / virology*
  • Liver Function Tests
  • Male
  • Middle Aged
  • Protease Inhibitors / administration & dosage
  • Protease Inhibitors / adverse effects*
  • Simeprevir / administration & dosage
  • Simeprevir / adverse effects*
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Protease Inhibitors
  • Simeprevir