[Evaluation of atopy risk factors during the first year of life. Multicentric study]

Pediatr Med Chir. 1989 Jul-Aug;11(4):403-9.
[Article in Italian]

Abstract

The AA studied 406 newborn babies during the 1st year of life in order to verify the correlation between atopy risk factors and the appearance of early symptoms, particularly gastroenteric (GE). The results obtained did not demonstrate a significant difference concerning the blood cord IgE level and subsequent appearance of food allergy symptoms, whereas positive familiarity showed a better correlation. No significant difference was observed between breast--or formula--fed infants, or between those weaned before or after the 5th month of life. The comparison of dietary regimen adopted during the 1st quarter in the asymptomatic and atopic children respectively, demonstrated that the presence of predisposing factors influences the appearance of GE symptoms much more than the diet in itself. An allergologic study, randomly performed by Prick-test in 156 cases and by RAST in 200 cases, showed a prevalent, positive response with RAST technique in symptomatic children.

Publication types

  • Clinical Trial
  • English Abstract
  • Multicenter Study

MeSH terms

  • Follow-Up Studies
  • Food Hypersensitivity / blood
  • Food Hypersensitivity / complications
  • Food Hypersensitivity / immunology*
  • Humans
  • Hypersensitivity, Delayed / immunology
  • Hypersensitivity, Immediate / blood
  • Hypersensitivity, Immediate / complications
  • Hypersensitivity, Immediate / immunology*
  • Immunoglobulin E / analysis
  • Infant, Newborn
  • Multicenter Studies as Topic
  • Risk Factors
  • Skin Tests

Substances

  • Immunoglobulin E