Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride

Protein Cell. 2016 Apr;7(4):300-304. doi: 10.1007/s13238-016-0256-7.
No abstract available

Publication types

  • Letter

MeSH terms

  • Amiloride / analogs & derivatives*
  • Amiloride / chemistry
  • Amiloride / metabolism
  • Binding Sites
  • Genotype
  • Hepacivirus / genetics
  • Hepacivirus / metabolism*
  • Humans
  • Magnetic Resonance Spectroscopy
  • Molecular Dynamics Simulation
  • Protein Structure, Tertiary
  • Viral Proteins / antagonists & inhibitors
  • Viral Proteins / metabolism*

Substances

  • Viral Proteins
  • p7 protein, Hepatitis C virus
  • 5-(N,N-hexamethylene)amiloride
  • Amiloride