The role of debulking resections in giant malignant insulinoma is still controversial. Here, we report the case of a 49-year-old patient woman with a giant malignant symptomatic insulinoma, who underwent debulking surgery, realizing a total pancreatectomy, splenectomy, partial gastrectomy and cholecystectomy.
Keywords: Giant insulinoma; Insulinoma; Metastatic insulinoma; Neuroendocrine tumour; TNE.