Infection and Nonunion After Fasciotomy for Compartment Syndrome Associated With Tibia Fractures: A Matched Cohort Comparison

J Orthop Trauma. 2016 Jul;30(7):392-6. doi: 10.1097/BOT.0000000000000570.

Abstract

Objectives: The objective was to compare the rates of union and infection in patients treated with and without fasciotomy for acute compartment syndrome (ACS) in operatively managed tibia fractures.

Design: This was a retrospective review.

Setting: The study was conducted at both a Level 1 and Level II trauma center.

Patients/participants: Patients operated for tibial plateau fractures (group 1) and tibial shaft fractures (group 3) with ACS requiring fasciotomy were matched to patients without ACS (plateau: group 2, shaft: group 4) in a 1:3 ratio for age, sex, fracture pattern, and open/closed injury.

Intervention: Surgical treatment was provided with plates/screws (plateau fractures) or intramedullary rod (shaft fractures). Patients with ACS were treated with a 2-incision 4-compartment fasciotomy.

Main outcome measurements: Time to union and incidence of deep infection, nonunion, and delayed union.

Results: One hundred eighty-four patients were included-group 1: 23 patients, group 2: 69 patients, group 3: 23 patients, and group 4: 69 patients. Time to union averaged 26.8 weeks for groups 1 and 3 and 21.5 weeks for groups 2 and 4 (P > 0.05). Nonunion occurred in 20% for groups 1 and 3 and in 5% for groups 2 and 4 (P = 0.003). Deep infection developed in 20% for groups 1 and 3 and in 4% for groups 2 and 4 (P = 0.001). There was a significant increase in infection in group 1 versus group 2 and nonunion in group 3 versus group 4. There were significantly more smokers for those with fasciotomies (46%) than without (20%, P < 0.001), though all statistical results remained similar after a binary regression analysis.

Conclusion: Four-compartment fasciotomies in patients with tibial shaft or plateau fractures is associated with a significant increase in infection and nonunion.

Level of evidence: Prognostic level III. See Instructions for Authors for a complete description of levels of evidence.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age Distribution
  • Anterior Compartment Syndrome / etiology
  • Anterior Compartment Syndrome / surgery*
  • Case-Control Studies
  • Fasciotomy / adverse effects*
  • Fasciotomy / methods
  • Female
  • Follow-Up Studies
  • Fracture Fixation / adverse effects
  • Fracture Fixation / methods
  • Fractures, Open / complications
  • Fractures, Open / pathology
  • Fractures, Open / surgery
  • Fractures, Ununited / diagnosis
  • Fractures, Ununited / epidemiology*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Registries
  • Retrospective Studies
  • Risk Assessment
  • Sex Distribution
  • Surgical Wound Infection / diagnosis
  • Surgical Wound Infection / epidemiology*
  • Tibial Fractures / complications*
  • Tibial Fractures / pathology
  • Tibial Fractures / surgery*