Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and the spectrum of this disease includes simple liver steatosis, nonalcoholic steatohepatitis, liver fibrosis, and liver cirrhosis. At present, liver biopsy is still the gold standard for the diagnosis of NAFLD and can determine the degree of steatosis, inflammation grade, and fibrosis stage, but its clinical application is limited by its invasiveness and static nature. New diagnostic markers and noninvasive diagnostic methods have been reportedly recently, and the constant development of magnetic resonance imaging, transient elastography, and controlled attenuation parameter provides new methods for the noninvasive diagnosis of NAFLD.