Inhibition of Hedgehog signaling for the treatment of lymphoma and CLL: a phase II study from the LYSA

Ann Oncol. 2016 Jul;27(7):1349-50. doi: 10.1093/annonc/mdw138. Epub 2016 Mar 21.
No abstract available

Publication types

  • Clinical Trial, Phase II
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anilides / pharmacology
  • Anilides / therapeutic use*
  • Female
  • Hedgehog Proteins / antagonists & inhibitors*
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / diagnosis
  • Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
  • Lymphoma, Non-Hodgkin / diagnosis
  • Lymphoma, Non-Hodgkin / drug therapy*
  • Male
  • Middle Aged
  • Pyridines / pharmacology
  • Pyridines / therapeutic use*
  • Signal Transduction / drug effects*

Substances

  • Anilides
  • Hedgehog Proteins
  • HhAntag691
  • Pyridines

Associated data

  • EudraCT/2012-000757-31