Binding of chemical warfare agent simulants as guests in a coordination cage: contributions to binding and a fluorescence-based response

Christopher G P Taylor; Jerico R Piper; Michael D Ward

doi:10.1039/c6cc02021f

Binding of chemical warfare agent simulants as guests in a coordination cage: contributions to binding and a fluorescence-based response

Chem Commun (Camb). 2016 May 7;52(37):6225-8. doi: 10.1039/c6cc02021f. Epub 2016 Mar 29.

Authors

Christopher G P Taylor¹, Jerico R Piper, Michael D Ward

Affiliation

¹ Department of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK. [email protected].

PMID: 27020844
DOI: 10.1039/c6cc02021f

Abstract

Cubic coordination cages act as competent hosts for several alkyl phosphonates used as chemical warfare agent simulants; a range of cage/guest structures have been determined, contributions to guest binding analysed, and a fluorescent response to guest binding demonstrated.

MeSH terms

Binding Sites
Chemical Warfare Agents / chemistry*
Fluorescence*
Models, Molecular
Molecular Conformation
Organophosphorus Compounds / chemistry*

Substances

Chemical Warfare Agents
Organophosphorus Compounds