Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis

Am J Respir Cell Mol Biol. 2016 Apr;54(4):594-7. doi: 10.1165/rcmb.2015-0322LE.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminophenols / pharmacology*
  • Animals
  • Cystic Fibrosis / immunology
  • Cystic Fibrosis / metabolism*
  • Cystic Fibrosis / pathology
  • Cystic Fibrosis Transmembrane Conductance Regulator / metabolism*
  • Humans
  • Monocytes / immunology
  • Proteome / drug effects*
  • Quinolones / pharmacology*

Substances

  • Aminophenols
  • Proteome
  • Quinolones
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • ivacaftor