Ketone Bodies Signal Opportunistic Food-Seeking Activity

Amandine Chaix; Satchidananda Panda

doi:10.1016/j.tem.2016.03.014

Ketone Bodies Signal Opportunistic Food-Seeking Activity

Trends Endocrinol Metab. 2016 Jun;27(6):350-352. doi: 10.1016/j.tem.2016.03.014. Epub 2016 Mar 30.

Authors

Amandine Chaix¹, Satchidananda Panda²

Affiliations

¹ Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010, North Torrey Pines Road, La Jolla, CA 92037, USA.
² Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010, North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: [email protected].

Abstract

Food-seeking activity at a predictable time of the day is one of the fundamental 'opportunistic behaviors' for survival. The neural and molecular basis for such anticipatory activity is not clearly understood. However, a new report shows that, after several hours of fasting, liver-derived ketone bodies have a key role in this behavior.

Publication types

Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anticipation, Psychological / physiology
Appetitive Behavior / physiology
Fasting / physiology
Humans
Ketone Bodies / metabolism*
Liver / metabolism

Substances

Ketone Bodies

Abstract

Publication types

MeSH terms

Substances

Grants and funding