Safety and Efficacy of Minimally Invasive Acetabular Stabilization for Periacetabular Metastatic Disease with Thermal Ablation and Augmented Screw Fixation

J Vasc Interv Radiol. 2016 May;27(5):682-688.e1. doi: 10.1016/j.jvir.2016.01.142. Epub 2016 Apr 1.

Abstract

Purpose: To evaluate minimally invasive acetabular stabilization (MIAS) with thermal ablation and augmented screw fixation for impending or minimally displaced fractures of the acetabulum secondary to metastatic disease.

Materials and methods: Between February 2011 and July 2014, 13 consecutive patients underwent thermal ablation, percutaneous screw fixation, and polymethyl methacrylate augmentation for impending or nondisplaced fractures of the acetabulum secondary to metastatic disease. Functional outcomes were evaluated before and after the procedure using the Musculoskeletal Tumor Society (MSTS) scoring system. Complications, hospital length of stay, and eligibility for chemotherapy and radiation therapy were assessed.

Results: All procedures were technically successful with no major periprocedural complications. The mean total MSTS score improved from 23% ± 11 before MIAS to 51% ± 21 after MIAS (P < .05). The mean MSTS pain scores improved from 0% (all) to 32% ± 22 after MIAS (P < .05). The mean MSTS walking ability score improved from 22% ± 19 to 55% ± 26 after MIAS (P < .05). Two complications occurred; a patient had a minimally displaced fracture of the superior pubic ramus at the site of repair but remained ambulatory, and septic arthritis was diagnosed in another patient 12 months after repair. The average length of hospital stay was 2 days ± 3.6; six patients were discharged within 24 hours of the procedure. All patients were eligible for chemotherapy and radiation therapy immediately after the procedure.

Conclusions: MIAS is feasible, improves pain and mobility, and offers a minimally invasive alternative to open surgical reconstruction.

MeSH terms

  • Ablation Techniques* / adverse effects
  • Acetabulum / diagnostic imaging
  • Acetabulum / injuries
  • Acetabulum / physiopathology
  • Acetabulum / surgery*
  • Adult
  • Aged
  • Aged, 80 and over
  • Biomechanical Phenomena
  • Bone Cements
  • Bone Neoplasms / complications
  • Bone Neoplasms / secondary
  • Bone Neoplasms / surgery*
  • Bone Screws*
  • Chemotherapy, Adjuvant
  • Female
  • Fracture Fixation, Internal / adverse effects
  • Fracture Fixation, Internal / instrumentation*
  • Fracture Healing
  • Fractures, Spontaneous / diagnostic imaging
  • Fractures, Spontaneous / etiology
  • Fractures, Spontaneous / physiopathology
  • Fractures, Spontaneous / surgery*
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Polymethyl Methacrylate / administration & dosage
  • Radiotherapy, Adjuvant
  • Recovery of Function
  • Retrospective Studies
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Bone Cements
  • Polymethyl Methacrylate