HLA-A, -B, -C, -DQA1, -DQB1, -DRB1, -E, -F and -G genotyping of 130 individuals from Terceira Island, Azores, Portugal

Hum Immunol. 2016 Jun;77(6):445-6. doi: 10.1016/j.humimm.2016.03.008. Epub 2016 Apr 1.

Abstract

One hundred and thirty unrelated Azorean individuals were randomly selected to study the frequencies of high-resolution HLA alleles and haplotypes in the Azorean (Terceira) population. HLA-A, -B, -Cw, -DRB1, -DQA1 and -DQB1 high-resolution genotyping was performed by polymerase chain reaction using commercial kits. HLA-E, -F and -G alleles, were genotyped by sequence-based typing. All loci were in HWE, showing no locus-level deviations. The genotype data is available in the Allele Frequencies Net Database under the population name "Azores Terceira Island" and the identifier (AFND112579).

Keywords: Azores; HLA alleles; Haplotypes; Portugal.

MeSH terms

  • Alleles
  • Azores
  • Gene Frequency*
  • Genotype
  • HLA Antigens / genetics*
  • HLA-A Antigens / genetics
  • HLA-B Antigens / genetics
  • HLA-C Antigens / genetics
  • HLA-DQ Antigens / genetics
  • HLA-DQ alpha-Chains / genetics
  • HLA-DQ beta-Chains / genetics
  • HLA-DRB1 Chains / genetics
  • HLA-E Antigens
  • HLA-G Antigens / genetics
  • Histocompatibility Antigens Class I / genetics
  • Humans
  • Portugal

Substances

  • HLA Antigens
  • HLA-A Antigens
  • HLA-B Antigens
  • HLA-C Antigens
  • HLA-DQ Antigens
  • HLA-DQ alpha-Chains
  • HLA-DQ beta-Chains
  • HLA-DRB1 Chains
  • HLA-F antigens
  • HLA-G Antigens
  • Histocompatibility Antigens Class I