Primary Vaginal Adenosarcoma With Sarcomatous Overgrowth Arising in Recurrent Endometriosis: Feasibility of Laparoscopic Treatment and Review of the Literature

J Minim Invasive Gynecol. 2016 Jul-Aug;23(5):833-8. doi: 10.1016/j.jmig.2016.03.019. Epub 2016 Mar 31.

Abstract

We report a case of a primary vaginal adenosarcoma with sarcomatous overgrowth in a postmenopausal 58-year-old woman with recurrent endometriosis. In the past 5 years she underwent several biopsies of a polypoid lesion on the vaginal cuff, and the last histologic examination of the biopsy showed an adenosarcoma with "sarcomatous overgrowth" in a background of endometriosis. There was no evidence of distant metastatic disease on the diagnostic workup, and we performed a laparoscopy to remove the pelvic mass. We reviewed the literature on the electronic databases Medline, Embase, and Science Direct on articles published in English from 1990 to 2015. We identified 5 articles in which the surgical treatment was performed via a laparotomic approach. The present case is the first in the literature to report feasibility of laparoscopic treatment for this kind of pathology with a detailed description of the surgical technique.

Keywords: Endometriosis; Laparoscopy; Malignant transformation; Sarcomatous overgrowth; Vaginal adenosarcoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenosarcoma / pathology
  • Adenosarcoma / surgery*
  • Cell Transformation, Neoplastic
  • Endometriosis / complications*
  • Endometriosis / pathology
  • Endometriosis / surgery
  • Feasibility Studies
  • Female
  • Humans
  • Laparoscopy*
  • Middle Aged
  • Recurrence
  • Ultrasonography, Doppler, Color
  • Vaginal Neoplasms / pathology
  • Vaginal Neoplasms / surgery*