Mirror therapy in children with hemiparesis: a randomized observer-blinded trial

Dev Med Child Neurol. 2016 Sep;58(9):970-8. doi: 10.1111/dmcn.13117. Epub 2016 Apr 5.

Abstract

Aim: To determine the efficacy of mirror therapy in children with hemiparesis.

Method: The design was an observer-blinded parallel-group randomized controlled trial (International Standard Randomised Controlled Trial Number 48748291). Randomization was computer-generated, 1:1 allocation to mirror therapy or comparison groups. The settings were home-based intervention and tertiary centre assessments. Participants were 90 children with hemiparesis aged 7 to 17 years. Intervention was 15 minutes per day of simultaneous arm training, 5 days a week, for 5 weeks. The mirror therapy group used a mirror; those in the comparison group looked at their paretic limb. Assessments comprised measures of upper limb strength, function (Melbourne Assessment 2), daily performance (ABILHAND-Kids), and sensory function at weeks 0 (T0 ), 5 (T1 ), and 10 (T2 ).

Results: There were no significant differences in outcomes and their progression over time between the mirror therapy and comparison groups. Post-hoc intention-to-treat analyses showed significant improvements in both groups for grasp strength (T0 -T1 +12.6%), pinch strength (T0 -T2 +9.1%), upper limb function in terms of accuracy (T0 -T2 +2.7%) and fluency (T0 -T2 +5.0%), as well as daily performance (T0 -T2 +16.6%). Per protocol analyses showed additional improvements in dexterity (T0 -T2 +4.0%).

Interpretation: The use of the mirror illusion during therapy had no significant effect on treatment outcomes. However, 5 weeks of daily simultaneous arm training significantly improved paretic upper limb strength, function, and daily use.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Child
  • Disability Evaluation
  • Exercise Therapy / methods*
  • Factor Analysis, Statistical
  • Female
  • Follow-Up Studies
  • Humans
  • Illusions / physiology*
  • Intention
  • Male
  • Paresis / physiopathology*
  • Paresis / psychology
  • Paresis / rehabilitation*
  • Single-Blind Method
  • Treatment Outcome
  • Upper Extremity / physiopathology